He and his team have successfully tested their compound on animal models, as they report in the Oct. Jayachandran Kizhakkedathu, an Associate Professor in the Department of Pathology,sought to develop a synthetic antidote that would work with all heparins used in clinics. In addition, two of the most commonly prescribed varieties of heparin have no medically approved antidote. But there are about a dozen approved heparin products on the market, and none of the reversal drugs work with all varieties of heparins. Patients often need an antidote to heparin to prevent serious bleeding, especially during surgery. Photo by Martin DeeĪ Faculty of Medicine researcher is developing a universal antidote to the many varieties of heparin, the blood thinner used in major surgeries and treatment of heart disease.
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